1P-LSD

1p lsd 

1P-LSD for sale. In mice 1PLSD, Produces LSD-like effects with 38% the potency of LSD and it is therefore classed as a serotonergic hallucinogen.However, 1P-LSD itself is unable to bind to the serotenergic 5-HT_2A receptors. But since LSD is detected when 1P-LSD is incubated in human serum, 1P-LSD may act, at least in part, as a prodrug for LSD.

What is 1P LSD? 

1P LSD is short for 1-propionyl-lysergic acid diethylamide. As an analogue of LSD and homologue of ALD-52, it is classified as a psychedelic substance of the lysergamide class. 1P LSD is made by adding a propionyl group to the nitrogen molecule of LSD’s indole. In other words, it is the same substance as LSD with an additional chemical chain. Recently, it has become available as a research chemical in the form of blotters and powdered material. Typically, it takes 45-90 minutes to begin to feel the effects and lasts anywhere between 8-12 hours.

Pharmacology

Though 1P LSD functions similarly to LSD, too little research exists to make definitive claims. However, due to its chemical similarities, it functions as a serotonergic substance. It binds to the 5-HT serotonin receptors in the brain or body. The way LSD binds to the 5-HT2A receptor, in particular, causes a cross-activation of the 5-HT2A receptor heteromer. In other words, this relationship produces long-lasting psychedelic effects. 1P-LSD probably binds with the monoamine receptors responsible for dopamine and norepinephrine but, again, little data exists to back up these claims.

A study from 2015 indicated that 1P-LSD shows 38% the potency of LSD in mice, though the drug did exhibit LSD-like behavior. There is a theory that 1P-LSD may act as a prodrug for LSD, which would mean that it turns into LSD once metabolized in the body. However, more studies need to be conducted in order to determine how 1P-LSD functions and if it is capable of producing its own psychedelic effects.1p lsd for sale.

1P LSD vs LSD: What’s the Difference?

Subjectively speaking, users claim that the effects are more or less identical. However, a recent study investigated the similarities and differences in mice. Researchers found that 1P LSD shows 38% of the potency of LSD. This could indicate that 1P LSD is a prodrug, which means that it metabolizes into LSD in the body. The process could make 1P LSD weaker in comparison as well as slower to take effect. According to users, however, this does not seem to accurately reflect their experiences.1p LSD For Sale

The main differences include:

• Molecular weight: LSD, 320g/mol | 1P LSD, 380g/mol.
• 1P LSD: has three more carbons and one more oxygen in its molecular structure than LSD has.
• Legalities: LSD is an illegal drug in most countries. 1P LSD is a research chemical and is legal.
• Effects: 1P LSD may be more stimulating and fast-paced in regard to its physical and cognitive effects. However, overall, the average user expresses that they cannot tell the difference.

Overall, more scientific research needs to be done in order to determine how they compare to and differ from one another.

Benefits & Risks 1p lsd for sale.

Concerning the risks and benefits of 1P LSD, know how much you’re taking and what kind of experience you are looking for. If you’re new to psychedelics, doing it alone might not be advisable. An unfavorable set and setting could potentiate a series of issues.

If you’re taking medications or have a pre-existing condition, particularly those defined as cardiovascular or mental, then consult a trained physician or expert before taking any substance. There is a risk of vasoconstriction in the heart, and psychosis for bipolar disorder and schizophrenia. Furthermore, mixing certain pharmaceutical drugs may counter-interact with 1P LSD as well. Benzodiazepine tends to lower the effectiveness of lysergic acid diethylamide and any other psychedelic substance. Mixing certain antidepressants with LSD can result in serotonin syndrome due to an overload of serotonin in the central nervous system.

Other concerns include HPPD and PTSD. HPPD, or hallucinogen persisting perception disorder, is a disorder where users see “visual snow” long after the trip has ended. This can disrupt an individual’s ability to perform regular tasks due to the distraction caused by visual snow. In more extreme cases HPPD can result in severe hallucinations for prolonged periods of time.

All these factors indicate the need for preparation and forethought to reduce the risks of taking 1P LSD.

Aside from that, the risks of 1P LSD are technically unknown. Since science governs the area of medicine, when we speak about a substance we cannot make definite claims about them unless backed up by science. Personal accounts, even if there are thousands, cannot technically be credited as factual.  However, 1P LSD appears to function like LSD, which would make it a relatively low-risk drug since scientific evidence on LSD shows that there are minimal adverse effects.

Top Reported Benefits

Recently, a resurged interest in LSD has led scientists to reconsider the studies that were conducted in the 50s and 60s. Those investigations primarily focused on treating depression, post-traumatic stress disorder, drug dependency, and reducing anxiety in end-of-life patients. Since the effects are similar to LSD, it might be able to address these issues and their associated symptoms.

The top reported benefits include:

• Dissolution of the ego.
• A decrease in anxiety and depression.
• Euphoria.
• Spiritual enhancement and feelings of unity.

Is 1P LSD Legal?

1P LSD is available as a research chemical but is illegal in thirteen countries: Denmark, Finland, Germany, Estonia, Japan, Latvia, Lithuania, Norway, Sweden (listed as health hazard), and Switzerland. Romania classifies 1P LSD, but it is not technically illegal. In the United Kingdom, 1P-LSD may be illegal under the Psychoactive Substances Act. In the United States, 1P LSD is not controlled at the federal level. However, it could be considered an analogue to LSD in which case it would be illegal under the Federal Analogue Act.

FAQ

How long does 1P LSD Trip last?

The trip can last anywhere between 8-12 hours.

When was 1PLSD Synthesized?

Good question. That remains unknown, but we do know that it appeared online as a designer drug in 2015.

What is the High Like on 1PLSD?

The high on 1P LSD is similar to LSD. It is a serotonergic substance, which means it’s a stimulating high that enhances feelings of euphoria and your experience of the environment. Not everyone has visuals but they tend to be a common experience.

How Long Does it Take for 1PLSD to Kick In?

It usually takes around 45-90 minutes to begin to feel the effects.

Does 1PLSD Show Up on a Drug Test?

1P LSD will only show up in an LSD drug test. LSD only shows up a maximum of 48 hours after ingestion in urine, not in hair.

Do You Have Real 1PLSD ?

It is always a good idea to test your substances! If you use an Ehrlich’s reagent test, it’ll turn purple. On a marquis reagent test, it varies. Some results say dark green. Erowid would indicate that it’s real with the response: “no reaction.”

Does 1PLSD have a Comedown?

The comedown is between 2-4 hours with after effects lasting about two hours. However, the comedown can last up to 24 hours.1psd

United Kingdom

Although not explicitly listed under the Misuse of Drugs Act 1971, 1P-LSD may be covered in the UK under the Psychoactive Substances Act.

United States

While 1P-LSD is not controlled at the federal level in the United States, it is possible that 1PLSD could be considered as an analogue of LSD, in which case trade or possession with intent for human consumption could be prosecuted under the Federal Analogue Act.Home

1P-LSD or 1-propionyl-lysergic acid diethylamide is a psychedelic drug of the lysergamide class that is a derivative and functional analogue of LSD and a homologue of ALD-52. It has been sold online as a designer drug since 2015. It modifies the LSD molecule by adding a propionyl group to the nitrogen molecule of LSD’s indole. 1p lsd for sale.

In mice, 1P-LSD produces LSD-like effects with 38% the potency of LSD and it is therefore classed as a serotonergic hallucinogen. However, 1P-LSD itself is unable to bind to the serotenergic 5-HT_2A receptors. But since LSD is detected when 1P-LSD is incubated in human serum, 1P-LSD may act, at least in part, as a pro-drug for LSD